Research Program. Precision Nutrition and Cancer
Clinical Oncology Group
Group leader: Dr. Enrique Casado Sánz and Dr. Jaime Feliú Batle
Objectives: Cancer is a complex disease whose characteristics, prognosis and response to different treatments depend on several factors, which makes it imperative that cancer research must be done in a multidisciplinary way and with the joint effort of many researchers.
Under the premise that diet and lifestyle are key factors in both cancer prevention and treatment, our line of research focused on cancer-oriented nutrigenomics aims to deepen the knowledge of this pathology by studying highly efficient products and personalized strategies focused on the implementation of a Precision Nutrition that complements the individualized cancer treatments. To do this, we design and carry out clinical trials and nutritional studies that seek to find better ways to prevent, diagnose and treat cancer.
Our goal is to efficiently apply the knowledge of cellular, molecular, physiological, chemical or genetic processes to the search of more effective treatments or prevention and diagnostic techniques that improve the quality of life of the patients with whom we work.
Collaborator in the Precision Nutrition and Cancer Lab
Dr. Enrique Casado Sánz
Associate researcher, IMDEA Food. Group Leader of the Clinical Oncology Group.
Dr. Enrique Casado Sánz: Enrique Casado finished his undergraduateb studies in Medicine and Surgery (1992) and Biohealth Sciences (1993) in Complutense University of Madrid (Universidad Complutense de Madrid) (UCM). He obtained the Degree of Doctor of Medicine (1994) with Extraordinary Prize granted by UCM. He did his medical residency in La Paz University Hospital (Hospital Universitario de la Paz) (1993-97) and Master’s Degree in Palliative Care (1997) in Universidad Autónoma de Madrid (UAM), in combination with extended postdoctoral internships in University of Alabama (Birmingham) and University of California (San Francisco). He was the attending physician of Medical Oncology in gastrointestinal and thoracic cancer and laboratory coordinator for the Translational Oncology Group of Hospital Universitario de la Paz (Madrid), He is an associate professor of
UAM and visiting professor of UCM. He is currently the Director of the Medical Oncology Department at the Hospital Universitario Infanta Sofía (HUIS) de Madrid, Coordinating Professor of Oncology in the Universidad Europea de Madrid and Precision Oncology Laboratory (HUIS) Director. He has received 7 awards in recognition of his research work from institutions as prestigious as the American Society of Clinical Oncology.
Dr. Jaime Feliú Batlle
Associate researcher, IMDEA Food. Group Leader of the Clinical Oncology Group.
Dr. Jaime Feliú Batlle holds a Degree in Medicine and Surgery from Universidad Complutense de Madrid issued in 1982. He specialized in Medical Oncology in Hospital Universitario de la Paz, where he is currently the Director of Medical Oncology Department. He is a professor of Oncology in the Medicine Area of Universidad Autónoma de Madrid (UAM) and Director of Master’s Degree in Palliative Care and Treatments for Cancer Patient Support of UAM. Furthermore, he is the current president of the Multidisciplinary Spanish Group of Digestive Cancer (GEMCAD).He has participated as a principal investigator or co-investigator in more than 70 phase I, II and III trials. He has written or co-written more than 200 articles for national and international journals, more than 60 book chapters and has presented a large number of communications in national and international congresses.
Members
Dr. Ana María Jiménez Gordo
Associate researcher, IMDEA Food.
Graduated in Surgery and Medicine at Universidad Autonoma Madrid (1994). Specialty in Medical Oncology at Hospital Universitario La Paz (1998). PhD in Medicine at Universidad Autonoma Madrid (2004). Master in Palliative Care of Neoplastic Patient at Hospital La Paz (1998). Master in Molecular Oncology at CNIO (2009). Associate Profesor in Oncology at Universidad Europea Madrid from 2013. She has worked as Medical Oncologist in Hospital La Paz (1990- 2000), Hospital Alcorcon (2000-2005), Hospital Getafe (2005-2013) and Hospital Infanta Sofía from 2013. Pfeizer Fundation Prize of Clinical Investigation in 2012. She has more than 80 national and international publications, congress communications and book chapters. She is member of Spanish Society of Clinical Oncology and has collaborated in several work groups of long cancer survivors, translational investigation, geriatric Oncology and doing some Clinical Guideliness. Currently his line of research focuses on colorectal cancer, and collaborates in several clinical trials promoted by IMDEA Food.
Dr. María Sereno Moyano
Associate researcher, IMDEA Food
María Sereno finished her undergraduate studies in Medicine and Surgery (1999) in Universidad Autónoma de Madrid (UAM). She did her medical residency in La Paz University Hospital (2000-2003) and a Master’s Degree in Palliative Care (1997) in Universidad Autonoma de Madrid (UAM). She obtained the Degree of Doctor of Medicine (2005). She did a postdoctoral internship in Thoracic Program with Prof. S. Antonia in Moffit Comprenhensive Cancer Center in South Florida University (Tampa, Florida). She did a Master’s Degree in Molecular Oncology in the Oncology Research National Cancer Institute (2007-2009) in Madrid and another Master’s Degree in Immunooncology in Medical Department in Alcalá University (2017). She was the attending physician of Medical Oncology in Gastrointestinal and Thoracic Cancer unit from 2004-2008 and then, she moved to Infanta Sofía University Hospital (San Sebastian de Los Reyes, Madrid), where she is working in Thoracic and Genitourinary Tumors section. She is associate professor in European University of Madrid (UEM). She had published several papers and has participated in different traslational oncology projects, some of them with public support, as FIS and Plan Nacional. Currently his line of research focuses on lung cancer.
Dr. César Gómez Raposo
Associate researcher, IMDEA Food
César Gómez Raposo obtained his Medicine Degree at Universidad Autónoma de Madrid in 2002 and later his Medical Oncology speciality at Hospital Universitario La Paz in 2007. He performed his doctoral thesis (Excellent Cum Laude) in 2012 focused on ovarian cancer. Since 2008 he worked as medical oncologist at Hospital Universitario Infanta Sofía in San Sebastián de los Reyes, mainly in breast and gynecological cancer. As a result of this activity has participated in more than 25 papers published in peer reviewed medical or scientifi c journals, and has taken part in in- ternational clinical trials in breast and gynecological cancer. Currently, her line of research focuses on breast cancer and gynecological cancer, and leads several clinical trials that relate diet with prognostic and predictive factors of response to cancer treatment.
Dr. Juan Moreno Rubio
Postdoctoral researcher, IMDEA Food
Senior researcher in the Clinical Oncology Group (“Precision Nutrition and Cancer” Program) of IMDEA food. Coordinator of the Laboratory of Precision Oncology (POL) of the Infanta Sofía University Hospital (HUIS). Degree in Molecular Biology and Biochemistry from the Autonomous University of Madrid in 2004, and Doctorate in Biochemistry, Molecular Biology and Biomedicine (Excellent Cum Laude) by the Autonomous University of Madrid in 2010 with award for the best doctoral thesis (IISFJD). Formerly coordinator of the Laboratory of Translational Oncology at the La Paz University Hospital (HULP, IdiPaz, group 32). Author or co-author in more than 27 articles in international journals, registered 3 patents and researcher in multiple studies and competitive clinical and translational projects. Currently focused on efficiently and quickly transform the knowledge obtained from basic research in clinical applications that result in health benefits.
Email: juan.moreno@imdea.org
Phone: +34 91 727 81 00
Silvia Cruz Gil
Lab Technician
Silvia Cruz Gil obtained her Biochemistry Degree at Universidad Complutense de Madrid in 2013. During the last two years of her degree she collaborated with the Biochemistry II Department at Pharmacy School in Universidad Complutense de Madrid studying the molecular biology of hepatocellular carcinoma. Later, she continued her training by obtaining a Master in Molecular Biosciences at Universidad Autónoma de Madrid in 2014. Meanwhile, Silvia joined ALGENEX (Alternative Gene Expression S.L.) in association with I.N.I.A. (National Institute of Agricultural and Food Research and Technology) for an internship. During this period she worked in the development of vectored vaccines. In October 2014, she started studies conductive to her PhD Degree at IMDEA Food Institute in the Molecular Oncology Group. Her research primarily focuses on the role of the lipid metabolism in tumor progression. In April 2016 she obtained a Boehringer Ingelheim Travel Grant to perform a short research stage in the University Hospital Carl Gustav Carus(Dresden, Germany) to learn organoids technique under the supervision of Dr. Daniel Stange. Her thesis oral defense will be held at the beginning of 2019 titled “Lipid metabolism alterations in colorectal cancer: potential clinical relevance in the prognosis of the disease”.
Email: silvia.cruz@imdea.org
Phone: +34 91 727 81 00
| most relevant publications |
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| main research grants |
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Principal Investigator: Enrique Casado Sáenz ___________ Principal Investigator: Enrique Casado Sáenz ___________ Principal Investigator: María Sereno Moyano ___________ Principal Investigator: Jaime Feliu Batlle ___________ Principal Investigator: Guillermo Reglero Co-Participant Institutions: Hospital Universitario Infanta Sofía, Hospital Universitario La Paz. ___________ |
